Home / ... / Guidance and Resources for Assessments / Green Screen Supporting Lists / Lists for Reproductive and Developmental Toxicity

Lists for Reproductive and Developmental Toxicity


Specified Lists for Reproductive and Developmental Toxicity

DRAFT ONLY (Dec, 2009)

Placeholder

List Abbreviation List Type   List Category Green Screen Hazard Green Screen Benchmark
NIOSH Authoritative A Occupational Cancer H 1
NTP-C Authoritative A Known to be a human carcinogen H 1
NTP-C Authoritative A Reasonably Anticipated to be a human carcinogen H 1
NTP-C Authoritative A Chemicals of high concern H 1
SVHC Authoritative A Extremely Hazardous Substance, may be Green Screen vH or H vH 1
IRIS (1999, 2005) Authoritative A Carcinogenic to humans H 1
IRIS (1999, 2005) Authoritative A Likely to be carcinogenic to humans H 1
IRIS (2005) Authoritative B Suggestive evidence of carcinogenic potential M 2
IRIS (1999, 2005) Authoritative A Not likely to be carcinogenic to humans L N/A
IRIS (1999) Authoritative B Suggestive evidence of carcinogenicity, but not sufficient to assess human carcinogenic potential M 2
IRIS (1996) Authoritative A Known/likely human carcinogen H 1
IRIS (1986) Authoritative A Group A - Human Carcinogen H 1
IRIS (1986) Authoritative A Group B1 - Probably human carcinogen H 1
IRIS (1986) Authoritative A Group B2 - Probably human carcinogen H 1
IRIS (1986) Authoritative B Group C - “Possible human carcinogen” M 2
IRIS (1986) Reference   Group D – “Not classifiable as to human carcinogenicity”? (can be either not likely or a data gap) Unknown  
IRIS (1986) Authoritative A Group E - “Evidence of non-carcinogenicity to humans” L N/A
IARC Authoritative A Group 1: Agent is carcinogenic to humans H 1
IARC Authoritative A Group 2A: Agent is probably carcinogenic to humans H 1
IARC Authoritative B Group 2b: Possibly carcinogenic to humans M 2
IARC Reference   Group 3: Not classifiable as to carcinogenicity to humans Unknown N/A
IARC Authoritative A Group 4: Probably not carcinogenic to humans L N/A
PROP 65 Authoritative A Known to the state to cause cancer H 1
PROP 65 Authoritative A Known to the state to cause reproductive effects H 1
EU CMR List Authoritative A Carcinogen Category 1: “known” H 1
EU CMR List Authoritative A Carcinogen Category 2: “should be considered carcinogenic to humans” H 1
EU CMR List Authoritative B Carcinogen Category 3: “possibly carcinogenic to humans” (listed as Carc. Cat. 3) M 2
EU CMR List Authoritative A Mutagen Category 1: “Substances known to be mutagenic to man” H 1
EU CMR List Authoritative A Mutagen Category 2: “Substances which should be regarded as if they are mutagenic to man” H 1
EU CMR List Authoritative B Mutagen Category 3: Possible M 2
EU CMR List Authoritative A Reproduction Category 1: “known” to impair fertility in humans or cause developmental toxicity in humans” H 1
EU CMR List Authoritative A Reproduction Category 2: “should be regarded as if” they impair fertility to humans or cause developmental toxicity to humans” H 1
EU CMR List Authoritative B Reproduction Category 3: possible M 2
G&L Screening A Developmental Neurotoxicant H 1
G&L Screening A Neurotoxicant M 2
EU ED Screening A Category 1 (“at least one in-vivo study providing clear evidence for endocrine disruption in at least one species using intact animals”), H 2
EU ED Screening A Category 2 (“Potential for endocrine disruption. In-vitro data indicating potential for endocrine disruption in intact organisms. Also includes effects in-vivo that may, or may not, be ED-mediated.”) M 2
EU ED Screening B Category 3a (“No scientific basis for inclusion in list; ED Studies available but no indication of ED effects" L  
EU ED Reference   Category 3b (“Substances with no or insufficient data gathered") Unknown  
EU DSD Authoritative A R45 “May cause cancer” H 1
EU DSD Authoritative A R49 “May cause cancer by inhalation” H 1
EU DSD Authoritative B R40 “Limited Evidence of Carcinogenic Effects” M 2
EU DSD Authoritative A R46 “May cause heritable genetic damage“ H 1
EU DSD Authoritative B R68 “May cause irreversible effects“ M 2
EU DSD Authoritative A R60 “May impair fertility” H 1
EU DSD Authoritative A R61 “May cause harm to the unborn child” H 1
EU DSD Authoritative B R62 “Possible risk of impaired fertility” M 2
EU DSD Authoritative B R63 “Possible risk of harm to the unborn child” M 2
EU DSD Authoritative B R64 “May cause harm to breastfed babies” M 2

See definitions of list abbreviations



     RSS of this page